Full Stack Software Developer — PHP / Web Applications
Position Overview
We are seeking a Full Stack Software Developer to support the development and maintenance of our proprietary web-based electronic data capture (eDC) application and related systems.
The ideal candidate will have experience developing, troubleshooting, and maintaining PHP/MySQL web applications and be comfortable working with an existing production codebase. Responsibilities include developing customizations and enhancements, troubleshooting application issues, maintaining existing functionality, and supporting application modernization.
Because our software supports clinical research, experience with secure application development and validated/regulated systems is highly desirable.
Technology Environment
PHP · MySQL · JavaScript · HTML/CSS · Twig · Linux/Apache · AWS · Git
Required Qualifications
- 1+ year of professional PHP web development experience; 3+ years preferred.
- Strong SQL/MySQL experience, including relational database concepts, normalization, foreign keys, views, joins, and complex queries.
- Experience with Git or another version-control system.
- Strong working knowledge of HTML, JavaScript, and CSS.
- Experience developing and working with REST APIs and web-based services.
- Demonstrated experience debugging and maintaining existing production web applications, including front-end and back-end troubleshooting.
- Ability to understand an unfamiliar codebase, identify the source of problems, and implement well-controlled changes.
- Good understanding of web application security and secure coding practices.
Preferred Qualifications
Web Development & Tools
- Experience with Composer and npm dependency management.
- Experience with Webpack or similar JavaScript bundlers.
- Experience with the Twig templating engine.
- Experience using Chrome Developer Tools, PHP Xdebug, application/server logs, and browser network tools for application troubleshooting.
- Experience modernizing legacy PHP applications or migrating applications to newer frameworks/architectures.
Linux / AWS
- Experience working in a Linux/LAMP environment, including Apache/httpd, PHP/PHP-FPM, SSH, and basic Linux troubleshooting.
- Experience working in AWS cloud environments, with familiarity with services such as EC2, RDS, S3, FSx, ALB, IAM, Systems Manager (SSM), and CodeCommit.
Validated / Regulated Systems
- Experience working within a controlled SDLC for validated or GxP-regulated systems, including requirements, risk assessments, requirements-to-test traceability, documented testing, IQ/OQ or equivalent qualification activities, defect/deviation management, change control, and controlled releases.
- Working knowledge of 21 CFR Part 11, particularly electronic records, electronic signatures, audit trails, access controls, data integrity, and controlled system changes.
Bonus Experience
- Experience working in clinical research, pharmaceutical, CRO, or other regulated environments.
- Familiarity with SAS (Statistical Analysis System) or clinical research data.
- Experience with AI-assisted software development or LLM/AI APIs.
Key Responsibilities
- Develop and maintain PHP-based web applications, including customizations, enhancements, and bug fixes.
- Troubleshoot issues across the front-end, back-end, database, and supporting infrastructure.
- Write and modify SQL queries and database functionality.
- Participate in code review and source-control processes.
- Support application modernization efforts.
- Follow established security, testing, documentation, and change-control procedures.
- Support testing and documentation associated with changes to validated systems.
- Collaborate with Development, IT, Data Management, Quality Assurance, and other technical personnel/stakeholders.
Please send resume and inquiries: careers@prosoftclinical.com